摘要
目的比较奥卡西平与卡马西平单药治疗儿童部分性癫的疗效。方法71例新诊断的儿童部分性癫患者按单双号顺序分为奥卡西平组(35例)和卡马西平组(36例),并给予相应的药物治疗;6个月后进行疗效评价,观察不良反应。结果奥卡西平组和卡马西平组分别有25例及29例完成6个月治疗;脑电图改善率分别为44.0%及44.8%;显效率分别为92.0%及86.2%;不良反应发生率分别为22.2%及41.2%,两组间比较差异无统计学意义(均P>0.05);卡马西平组2例出现严重不良反应。结论奥卡西平与卡马西平单药治疗新诊断的儿童部分性癫均有很好的疗效,不良反应及耐受性相似,但奥卡西平组未见严重的不良反应。
Objective To compare the efficacy of the single drug treatment with Oxcarbazepine and Carbamazepine on children with partial epilepse.Methods By the number of single or double,71 new diagnostic children with partial epilepse were divided into Oxcarbazepine group(35 cases)and Carbamazepine group(36 cases),and received the certain drug therapy.The efficacy was evaluated 6 months post treatment. The adverse reaction during the treatment was obseved.Results 25 cases in Oxcarbazepine group and 29 cases in Carbam...
出处
《临床神经病学杂志》
CAS
北大核心
2008年第6期452-453,共2页
Journal of Clinical Neurology
关键词
癫
奥卡西平
卡马西平
epilepse
Oxcarbazepine
Carbamazepine
