胃肠道间质瘤的诊断和治疗

Diagnosis and treatment of gastrointestinal stromal tumors

目的探讨胃肠道间质瘤的诊断和治疗方法。方法对1998～2007年收治的35例胃肠道间质瘤患者的临床表现、手术处理及病理结果进行回顾性分析。结果肿瘤多位于胃部,最多的临床表现为腹部隐痛不适。手术前74.2%(26/35)的病例有不同程度的误诊。均行外科手术切除。其中因复发而行2次手术者10例,3次手术者8例。随访时间6个月～5年,死亡8例。结论胃肠道间质瘤缺乏特异性临床表现,术前确诊率较低,其确诊依靠病理结果。目前胃肠道间质瘤的治疗仍以手术切除为主,对复发或远处转移者积极再次手术可延长生存期。

ObjectiveTo explore the diagnosis and treatment of gastrointestinal stromal tumors(GIST) Methods 35 patients with GIST in Wuxi Second hospital from 1998 to 2005 were retrospectively analyed. Results Stomach was the most frequent site for GIST. Abdominal pain was the most common symptom. Before operation,74.2%(26/35) of the cases were misdiagnosed. All of the cases underwent surgical resections.10 recurrent GIST patients received a second resection and 8 patients underwent three resections. Follow-up was mad...