5%葡萄糖加0.45%盐水溶液联合胃肠道补水抢救糖尿病非酮症性高渗昏迷的研究

Study of the mixture solution of 5% glucose and 0.45% saline with fluid supplement through gastrointestinal tract in treating patients with nonketotic hyperosmolar diabetic coma

目的探讨(5%葡萄糖+0.45%盐水)溶液+胃肠道补水抢救糖尿病非酮症性高渗昏迷的应用及其效果。方法分别采用静脉输注生理盐水+胃肠道补水以及应用(5%葡萄糖+0.45%盐水)溶液+胃肠道补水两种补液方式,观察两组生化改变、病情变化和死亡率。结果静脉输注(5%葡萄糖+0.45%盐水)溶液+胃肠道补水能使治疗24h后血钠及血浆渗透压下降更加明显,循环改善时间缩短,死亡率降低。结论静脉输注(5%葡萄糖+0.45%盐水)溶液+胃肠道补水抢救糖尿病非酮症性高渗昏迷疗效明显优于静脉输注生理盐水+胃肠道补水。

ObjectiveTo approach intravenous infusion of the mixture solution of 5% glucose and 0.45% saline(low sodium ion GNS,LSI-GNS) with fluid supplement through gastrointestinal tract(FSTGIT) in treating patients with nonketotic hyperosmolar diabetic coma(NHDC) and their effects. MethodPatients were treated with FSTGIT and normal saline,or FSTGIT and LSI-GNS respectively,and observe the two groups of patients in serum biochemical parameters and pathogenetic condition changes and mortality rate. ResultsIntravenous...