β-羟丁酸与血酮体测定在糖尿病酮症酸中毒中的应用与比较

Application and Comparison of beta-Hydroxy Butyric Acid and the Blood Ketone Body Determination in Diabetic Ketoacidosis

目的:探讨测定血清β-羟丁酸与血酮体定性分析在糖尿病酮症酸中毒(DKA)诊断中的应用及两者的比较意义。方法:对31例临床诊断为糖尿病酮症酸中毒患者血清进行β-羟丁酸酶法测定及应用亚硝基铁氰化钠法进行血酮体定性分析,并对两种结果进行比较。结果:β-羟丁酸在31例患者血清中全部升高,而血酮体定性分析阳性为23例,8例为阴性,差异具有非常显著性(P<0.01)。结论:检测β-羟丁酸有助于糖尿病酮症酸中毒的早期诊断和治疗,其敏感性高于传统的血酮体定性分析。

Objective To explore determination blood serum beta-hydroxy butyric acid and blood ketone body qualitative analysis in diabetic ketoacidosis(DKA)diagnosis application and both comparison significance.Methods Carries on beta-the hydroxy butyric acid determination with enzyme velocity method to 31 example clinical diagnoses for diabetic ketoacidosis patient blood serum and carries on the blood ketone body qualitative analysis using the nitroso group sodium ferricyanide method.Results beta-hydroxy butyric acid...