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VEGF-C在宫颈癌组织中的表达及其与临床病理特征的关系 被引量：1

Expression of VEGF-C in cervical carcinoma and its relation ship with clinical characters
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摘要 目的:在组织病理学水平探讨VEGF-C与宫颈浸润癌局部浸润、远处淋巴转移等的关系。方法:采用免疫组化LsAB法检测68例宫颈浸润癌组织、10例正常宫颈组织的石蜡标本中VEGF-C蛋白的表达;分析其与宫颈癌的临床分期、病理组织分级、淋巴结转移及间质浸润等病理特征的关系。结果:VEGF-C在正常组织中没有表达,在宫颈癌组织中高表达,并且与宫颈癌的临床分期、病理分级、淋巴转移、间质的浸润深度有关,而与组织病理类型无关。结论:宫颈癌组织中VEGF-C表达与宫颈癌的进展和淋巴转移有关。 Objective:To study VEGF-C in cervical carcinoma and its relation ship with depth of cervical infiltration and lymph node metastasis of cervical carcinoma.Methods:Immunohistochemistry was used to detect the expression of VEGF-C in formalin-fixed,paraffin-embedded specimens of 68 primary invasive cervical carcinoma,10 normal cervical tissue.It s relation ship with cervical carcinoma clinical stage,pathological grade,pathological subtye,lymph node metastasis,et al.clinicopathological factors was analysed.Resul...
作者 田小飞 彭芝兰
机构地区 陕西省肿瘤医院 华西第二医院
出处 《陕西医学杂志》 CAS 北大核心 2008年第11期1520-1523,共4页 Shaanxi Medical Journal
关键词 宫颈肿瘤/病理学 血管生成因子/免疫学 基因表达 免疫组织化学 肿瘤转移 Cervix neoplasms/pathology Angiogensis factor/immunology Gene expression Immunohistochemistry Neoplasm metastasis
分类号 R737.33 [医药卫生—肿瘤]
  • 相关文献

参考文献12

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二级参考文献13

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共引文献31

同被引文献16

  • 1李梅,毛福荣,曹学全,张蕾,陈奎生.VEGF-C在宫颈鳞癌组织中的表达及临床意义[J].肿瘤基础与临床,2007,20(2):127-128. 被引量：5
  • 2张璇,陈莉,顾晓梅,哓霄,鄂群.宫颈癌及其癌前病变组织NET-1基因蛋白的表达及意义[J].中国妇幼保健,2007,22(25):3582-3584. 被引量：5
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  • 10Pa&vonen K, Hrelli-Kuitunen N, Chilov D, et al. Novel hum&n v&scul&r endotheli&l growth f&ctors genes VEGF-B &nd V EC-F-C Ioc&lize to chromosomes 11 q5 &nd 4q54, respectively[J].Circul&tion,;996,95 (6): 1079-1082.

二级引证文献8

陕西医学杂志
2008年 第11期

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