期刊文献+

影响维持性血液透析心血管钙化的因素 被引量:3

The Factor of Cardiovascular Calcification in Hernodialysis Patients
下载PDF
导出
摘要 目的观察血液透析患者心血管钙化的发生情况,探讨可能心血管钙化的相关因素。方法收集郴州市第一人民医院血液透析患者,彩超对颈内劝脉、心脏瓣膜钙化测量,并检测骨调素(OPN)及C反应蛋白(CRP)、全段甲状旁骧激素(iPTH)等与心血管钙化相关的临床指标并进行分析。结果55例血液透析患者,有49%患者有颈内动脉钙化,其中钙化组和非钙化组的患者相比,年龄更大,男性比例更高;钙化组OPN、CRP、血磷明显高于非钙化组。结论血液透析患者普遍存在心血管钙化,与透析患者氧化应激、高血磷有关,OPN水平较好地反应心血管钙化。 Objective To observe the factors of cardiovascular calcification in hemodialysis patients.Methods Fifty-five hemodialysis patients were enrolled in this study.Vascular calcification was evaluated color duplex echocardiography of internal carotid artery and cardiac valve.Demographic and clinical data were collected.Plasma osteopontin and other parameters related to calcification were examined.Results Vascular calcification on ultrasound presented in 27 cases(49%)found to have calcification on internal caroti...
出处 《中国医药指南》 2008年第21期17-18,10,共3页 Guide of China Medicine
关键词 血液透析 彩色多普勒超声心动图 血管钙化 骨调素 Hemodialysis Color duplex echocardiography Cardiovascular calcification Osteopontin
  • 相关文献

参考文献13

  • 1[1]Sarnak MJ.Cardiovascular complications in chronic renal disease[J].Am J Kidney Dis,2003,41(5):11-17.
  • 2[2]Chert NX,Duan D,O'Neill KD,et al.The mechanisms of uremic serum-induced expression of bone matrix proteins in bovine vascular smooth muscle cells[J].Kidney Int.2006,70(6):1046-1053.
  • 3[3]Milliner DS,Zinsmeister AR,Lieberman E,et al.Soft tissuecalcification in pediatric patients with end stage renal disease[J].Kidney Int,1990,38:931.
  • 4[4]Kestenbaum B,Sampson JN,Rudser KD,et al.Serum phosphate levels and mortality risk among people with chronic kidney disease[J].J Am Soc Nephrol,2005,16(2):520-528.
  • 5[5]Jono S,McKee MD,Murry CE,et al.Phosphate regulation of vascular smooth muscle cell calcification[J].Circ Res,2000,87:10-17.
  • 6[6]Raggi P,Boulay A,Chasan-Taber S,et al.Cardiac calcification in adult hemodialysis patients.A link between endstage renal disease and cardiovascular disease?[J].J Am Coll Cardiol,2002,39(4):695-701.
  • 7[7]Ganesh SK,Stack AG,Levin NW,et al.Association of elevated serum PO(4),Ca×PO4 product,and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients[J].J Am Soc Nephrol,2001,12:2131-2138.
  • 8[8]Zimmermann J,Herrlinger S,Pruy A,et al.Inflammation enhances cardiovascular risk and mortality in hemodialysis patients[J].Kidney Int,1999,55:648-658.
  • 9[9]Ishimura E,Okuno S,Kitatani K,et al.C-reactive protein is a significant predictor of vascular calcification of both aorta and hand arteries[J].Semin Nephrol,2004,24(5):408-412.
  • 10[10]Warrier B,Mallipeddi R,Karla PK,et al.The functional role of C-reactive protein in aortic wall calcification[J].Cardiology,2005,104(2):57-64.

同被引文献45

引证文献3

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部