摘要
目的观察血液透析患者心血管钙化的发生情况,探讨可能心血管钙化的相关因素。方法收集郴州市第一人民医院血液透析患者,彩超对颈内劝脉、心脏瓣膜钙化测量,并检测骨调素(OPN)及C反应蛋白(CRP)、全段甲状旁骧激素(iPTH)等与心血管钙化相关的临床指标并进行分析。结果55例血液透析患者,有49%患者有颈内动脉钙化,其中钙化组和非钙化组的患者相比,年龄更大,男性比例更高;钙化组OPN、CRP、血磷明显高于非钙化组。结论血液透析患者普遍存在心血管钙化,与透析患者氧化应激、高血磷有关,OPN水平较好地反应心血管钙化。
Objective To observe the factors of cardiovascular calcification in hemodialysis patients.Methods Fifty-five hemodialysis patients were enrolled in this study.Vascular calcification was evaluated color duplex echocardiography of internal carotid artery and cardiac valve.Demographic and clinical data were collected.Plasma osteopontin and other parameters related to calcification were examined.Results Vascular calcification on ultrasound presented in 27 cases(49%)found to have calcification on internal caroti...
出处
《中国医药指南》
2008年第21期17-18,10,共3页
Guide of China Medicine
关键词
血液透析
彩色多普勒超声心动图
血管钙化
骨调素
Hemodialysis
Color duplex echocardiography
Cardiovascular calcification
Osteopontin