摘要
目的探讨柚肉黄酮的降脂作用。方法1.试验性高血脂模型法将40只昆明种小鼠随机分成5组,对照组、高脂饲料组(模型组)、不同含量柚肉黄酮+高脂饲料组(柚肉黄酮小、中、大剂量组)。2.测定柚肉黄酮对血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)含量以及动脉硬化指数(AI)的影响。3.离体胆固醇微胶粒形成实验。结果1.柚肉黄酮明显降低喂以高脂饲料小鼠血清TG、TC、HDL-C、LDL-C含量以及AI水平,提高高密度脂蛋白胆固醇(HDL-C)含量,且作用与柚肉黄酮剂量呈正相关。2.柚肉黄酮体外实验有轻度抑制胆固醇微胶粒形成的作用。结论柚肉黄酮有显著的降血脂效应,其机理可能与其减少肠道胆固醇的吸收相关。
Objective To research the inhibition of serum lipids by grapefruit flavonoids (FG). Methods 1.establishing experiment mice hyperlipidmia model: 40 mice were divided into five groups and fed with different diets: basal diet (control gruop), high lipids diet (model group ), high lipids and different doses GF supplemented diet (small、medium and large group of GF). 2. The experiment in forming cemented particle of cholesterol in vitro. Results 1. GF has obvious effective in reducing hyperlipemia mice serum the ...
出处
《中国中医药现代远程教育》
2008年第10期1164-1165,共2页
Chinese Medicine Modern Distance Education of China
关键词
柚肉黄酮
血脂
胆固醇微胶粒
GF
blood lipids
cemented particle of cholesterol
