腰椎间盘突出症危险因素的病例对照研究

A Case-Control study on the risk factors of lumbar disc herniation

目的探讨腰椎间盘突出症(lumbar disc herniation,LDH)的危险因素。方法采用1∶1配对病例对照研究方法,匹配条件为:性别、民族、地区、职业及年龄(±3岁)对LDH的危险因素进行研究,用自行设计的调查问卷采用面对面询问的方法收集资料,危险因素分析采用单因素和多因素条件logistic回归分析。结果在262对调查对象中,多因素分析发现脊柱负荷越大,LDH发生的危险性就越大(OR=2.885);调查对象的文化程度高(OR=1.935)、肥胖(OR=2.090)、偏好辛辣食物(OR=2.690)、睡床越软(OR=1.610)、居住环境潮湿(OR=2.351)、经常生活在一起的家庭成员数越少(OR=2.488)、一二级亲属中有该病的家族史(OR=2.349)都是LDH的危险因素。结论LDH的发生与生物因素、生活方式、脊柱负荷大小和社会心理因素等多个因素有关,应采取针对性的综合干预措施来控制和预防该病的发生。

【Objective】To estimate the risk factors of lumber disc herniation(LDH).【Methods】We carried out a 1∶1 case control study to examine the risk facts of LDH.The controls were matched with cases in the same sex,race,region,occupation and age group(less than 3 years old).Data were collected in face-to-face interviews using self-design questionnaire.Conditional univariate and multiple logistic regressions were used to analyze the data.【Results】A total of 262 pairs of subjects were investigated.The multiple logisti...