代谢综合征虚、实证型患者血小板功能变化的临床研究

Clinical Study of Platelet Function Changes of Patients With Asthenia and Sthenia Metabolic Syndrome

目的:研究代谢综合征虚、实证型患者血小板功能变化情况。方法:以南京军区福州总医院124例代谢综合征(MS)患者为研究对象,按中医辨证分为虚证组53例,实证组71例,以60例正常人为对照组,测定血浆6-酮-前列腺F1α、血栓素B2的水平。结果:3组之间的6-酮-前列腺素F1α水平存在显著差异:实证组与健康对照组、虚证组与健康对照组比较有非常显著差异(P<0.01),且实证组与虚证组比较亦有显著差异(P<0.05);3组之间的TXB2水平存在显著差异:实证组与健康对照组、虚证组与健康对照组比较有显著差异(P<0.05),且实证组与虚证组比较亦有显著差异(P<0.05)。结论:MS患者虚实证型的区别同时体现在血小板聚积作用增强、抑制血小板聚积作用减弱两方面。

Objective:To study platelet function changes of patients with asthenia and sthenia Metabolic Syndrome(MS).Method:124 MS patients in our hospital were selected as study objects,which were divided into asthenia group with 53 MS patients and sthenia group with 71 patients in accordance with TCM differentiation.Compared with a control group of 60 healthy persons,examination was conducted on the items of 6-KetoPGF1α and Thromboxane B2.Result:Amid the three groups,there was a significant difference in the level o...