β受体阻滞剂对起搏器置入心衰患者左室功能的影响

The Effect of β-Blockers on Ventricular Function in Patients with Heart Failure

目的:观察β受体阻滞剂在治疗心衰患者时对心室收缩功能的影响。方法:将安装起博器有心衰症状的左室收缩功能障碍的66例患者,起博频率调整为60次每分并随即分为两组,治疗组33例在接受ACEI或ARB,氨体舒通治疗稳定的基础上加用β受体阻滞剂治疗;对照组33例接受ACEI或ARB,氨体舒通治疗;疗程为9个月,治疗前后行心脏彩色多谱勒检查,测量左室射血分数。结果:治疗组与对照组比较,治疗组显著提高平均左室射血分数。结论:在不改变心率的条件下,β受体阻滞剂在治疗心衰患者时可维持心室收缩功能。

Objective:To evaluated the effect on ventricular function in patients with heart failure treated with β-blockers.Methods:Sixty-six patients in pacemaker-dependent patients with symptomatic left ventricular(LV)systolic dysfunction seted pacing rate at 60 ppm.Thirty-three patients treated by angiotensin-converting enzyme inhibitors or angiotensin receptor blockers,β-blockers,and spironolactone.Other 33 patients treated by angiotensin-converting enzyme inhibitors or angiotensin receptor blockers,and spironolac...