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罗汉参对小鼠通便作用的研究 被引量:14

Effect of Luohanshen on the feces excretion function in mice
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摘要 目的研究山东单县地产罗汉参对小鼠的通便作用。方法将小鼠随机平均分为小肠运动实验组和排便实验组,每一大组再随机平均分成5小组(空白对照组、模型对照组和低、中、高剂量组)。分别用基础饲料和含5%、10%、15%罗汉参的饲料喂养15 d后,模型对照组和3个剂量组用复方地芬诺酯建立小鼠便秘模型,采用小肠运动实验和排便实验的方法探讨罗汉参对便秘模型小鼠的通便作用。排便实验组的空白对照组和3个剂量组再饲养3 d后,采用排便实验的方法探讨罗汉参对正常小鼠排便功能的影响。结果小肠运动实验显示,与模型对照组比较,中、高剂量组的墨汁推进率增高(P<0.01,P<0.05)。便秘模型小鼠的排便实验显示,与模型对照组比较,低、中、高剂量组的首粒黑便排出时间缩短(P<0.01),低、中剂量组的5 h排便粒数增加(P<0.05)。正常小鼠的排便实验显示,与空白对照组相比,除低剂量组首粒黑便排出时间缩短(P<0.05),其余各组各指标差异均无统计学意义(P>0.05)。结论罗汉参对便秘模型小鼠具有通便作用,对正常小鼠无通便作用。 Objective To explore the effect of Luohanshen produced from Shan County of Shandong Province on the feces excretion function in mice.Methods Mice were randomly divided into the small intestine motor experiment group and the defecation experiment group.Then each group was randomly divided into five equal groups(the blank control group,the model control group,the low dose group,the middle dose group and the high dose group).Mice of the model control group and three dose groups had the constipation model estab...
出处 《山东大学学报(医学版)》 CAS 北大核心 2009年第2期95-98,共4页 Journal of Shandong University:Health Sciences
关键词 罗汉参 通便 便秘模型 小鼠 Luohanshen Feces excretion Constipation model Mice
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