乙醇提取樟芝菌粉三萜类化合物的动力学研究

Kinetics on Extraction of Triterpenoids from Antrodia camphorata

以Fick扩散第二定律为基础,建立樟芝菌粉三萜提取过程的动力学方程,并由此推算出提取的速率常数、活化能、相对萃余率、半衰期,以及内扩散系数等动力学函数值。结果表明:所得提取模型能较好地描述樟芝菌粉三萜类化合物提取的动态过程。樟芝菌粉三萜类化合物提取过程的动力学符合一级动力学方程,为内扩散控制动力学。本研究可为樟芝三萜类化合物提取的工艺设计及操作条件的选择提供有价值的理论依据。

The Fick s second law of diffusion was used to establish the kinetics equation of extracting triterpenoid parameters from Antrodia camphorata in submerged fermentation.The extraction process was analyzed to obtain kinetics parameters,such as K(rate constant),Ea(activation energy),y(yield),t1/2(half life)and Ds(internal diffusion coefficient).The results showed that the kinetics on the extraction of triterpenoids match the first-order rate equation,and the rate-determining step for extraction is the diffusio...