胃癌组织中RASSF2A基因启动子甲基化检测及其临床意义
被引量：1
摘要
目的:探讨胃癌中RASSF2A基因启动子甲基化特征。方法:采用甲基化特异性聚合酶链反应(MSP)检测34例胃癌患者癌组织和癌旁组织RASSF2A基因启动子甲基化情况。结果:胃癌组织RASSF2A基因甲基化发生率为24%,明显高于癌旁组织,差异有统计学意义(P<0.05)。RASSF2A基因甲基化与分化程度,转移等无明显相关。结论:RASSF2A基因甲基化是胃癌发生的频发分子事件,可能在胃癌发生起重要作用。
出处
《中国误诊学杂志》
CAS
2009年第4期791-792,共2页
Chinese Journal of Misdiagnostics
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