摘要
目的探讨肺隐球菌病的临床表现和影像学特点、诊断和治疗,以提高对本病的认识。方法回顾性分析我院2002年1月—2008年6月经病理确诊为肺隐球菌病住院患者15例,总结其临床表现、影像学特点、诊断方法及治疗情况。结果本组肺隐球菌病以中青年男性为主,既往有基础疾患8例(占53.3%)。主要临床症状有:咳嗽(10例,66.7%)、发热(6例,40.0%)、咳痰(5例,33.3%)。病变位于右肺12例,左肺7例,影像学以肿块结节型为主(12例,80.0%)。CT引导下经皮肺穿刺活检证实7例(46.7%),手术证实6例(40.0%),颈部淋巴结活检证实2例(13.3%)。病理诊断前误诊为肺结核4例(26.7%),周围型肺癌5例(33.3%),普通细菌感染4例(26.7%),误诊率达86.7%。6例(40.0%)经外科手术切除,1例术后发生隐球菌脑膜炎;9例(60.0%)经抗真菌药物治疗,7例患者痊愈或显效。结论肺隐球菌病多发生于中青年男性,临床表现无特异性,影像学改变以肿块结节型为主,误诊率高,确诊有赖于病理,尽早行CT引导下经皮肺穿刺活检是有价值的确诊手段,手术患者术后宜行足疗程全身抗真菌治疗。
Objective To investigate the clinical manifestations,imaging features,diagnosis and management of pulmonary cryptococcosis.MethodsFifteen patients with pulmonary cryptococcosis identified by pathological examination in our hospital from January 2002 to June 2008 were studied retrospectively.Clinical manifestations,imaging features,diagnostic methods and management were analyzed.ResultsSeven of the fifteen(46.7%)cases were between 20 and 45 years old;12(80.0%)were male;8 of 15 cases(53.3%)have underlying dis...
出处
《中国感染与化疗杂志》
CAS
2009年第1期67-69,共3页
Chinese Journal of Infection and Chemotherapy
关键词
肺隐球菌病
临床误诊
影像学表现
pulmonary cryptococcosis
clinical misdiagnosis
imaging feature
