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丹宁酸改性处理对戊二醛固定牛颈静脉管道理化特性的影响 被引量：5

Effect of Tannic Acid Treatment on the Physico-chemical Properties of Glutaraldehyde-fixed Bovine Jugular Vein
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摘要 目的评估丹宁酸改性处理对戊二醛固定牛颈静脉管道理化性质的影响。方法新鲜牛颈静脉分别经戊二醛固定(对照组)和戊二醛固定/丹宁酸改性处理后(研究组),采用热收缩温度、抗蛋白酶解性能、生物力学性能及傅立叶变换红外线光谱法进行理化性质评价。结果研究组牛颈静脉管壁的热收缩温度(P<0.01)、抗胶原纤维酶和抗弹性蛋白酶酶解性能(P<0.01)、管壁最大拉伸强度(P<0.01)及断裂伸长率(P<0.05)等指标均明显高于对照组,且管壁示红外线峰值偏移。结论丹宁酸改性处理可显著改善戊二醛固定牛颈静脉管道的理化性质。 Objective To evaluate the effects of tannic acid(TA) treatment on the physico-chemical properties of glutaraldehyde(Glut)-fixed bovine jugular vein(BJV).Methods Fresh BJVs were treated with Glut or Glut/TA,respectively.The shrinkage temperature,resistance to collagenase or elastase digestion,biomechanical properties,and molecular structure of these prepared BJVs were evaluated by Fourier transform infrared spectroscopy.Results TA treatment resulted in higher shrinkage temperature(P<0.01),higher resistanc...
作者 王德 周建业 胡盛寿 蒋虹 汪胜 李君
机构地区 中国医学科学院北京协和医学院阜外心血管病医院卫生部心血管疾病再生医学重点实验室
出处 《中国医学科学院学报》 CAS CSCD 北大核心 2009年第1期65-67,共3页 Acta Academiae Medicinae Sinicae
基金 北京市科委基金项目(Y0405003040291)~~
关键词 牛颈静脉 丹宁酸 弹力纤维 理化性质 bovine jugular vein tannic acid elastic fiber physico-chemical property
分类号 R318.08 [医药卫生—生物医学工程]
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参考文献1

二级参考文献5

  • 1李胜利,胡盛寿.带瓣牛颈静脉作为右室肺动脉连接管道的研究[J].中华胸心血管外科杂志,2004,20(4):248-249. 被引量：5
  • 2Dave HH, Kadner A, Berger F, et al. Early results of the bovine jugular vein graft used for reconstruction of the right ventricular outflow tract. Ann Thorac Surg, 2005,79:618-624.
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共引文献17

同被引文献46

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引证文献5

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中国医学科学院学报
2009年 第1期

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