我国东南部地区妇幼人群静脉血多氯联苯水平及危险性研究

Risk Assessment and Concentration Levels of PCBs in Venous Blood from Mothers and Children in Southeast China

目的研究废旧变压器拆解点周围妇女儿童多氯联苯(PCBs)暴露水平及危险性评价。方法以F地区为研究现场,选择该地区中心小学50名8~10岁学龄儿童和其母亲为研究对象,采集妇女儿童空腹外周静脉血,用Agilent 5973N GC-MSD超痕量分析方法检测其PCBs(13个异构体)含量及血液、尿液临床生化检验,并作调查问卷及健康体检,最后作危险度评价。结果妇女和儿童外周静脉血中多氯联苯几何均值分别达175.9 ng/g、191.6 ng/g类脂;健康体检,儿童龋齿率82%。结论该地区妇女儿童血液中的PCBs含量已经有一定的蓄积水平,并且二者有较好的线性关系(r=0.736 3)。危险度评价提示,妇女PCBs内暴露已处于临界水平,5名母亲血液中PCBs的水平超过了5μg/g。根据加拿大咨询专家D r.Andy G ilm en提供的PCBs指南标准,已有10%的妇女应该受到关注。

Objective To study the concentration levels and risk of polychlorinated biphenyls(PCBs)in human venous blood from mothers and children .Methods F region was selected as the study locale,and 50 students aged 8 to 10 and their mothers were chosen as study subjects.Their limosis venous blood was collected and the PCBs(13 isomers)was detected.Also the clinical biochemical test of their blood and urine was conducted,followed with the questionnaire research and health examination.Results The average content of PC...