摘要
目的观察中西医结合治疗系统性红斑狼疮(SLE)的远期疗效。方法采用随机分组的方法,治疗组74例用中药解毒诸法联合激素治疗,对照组74例只用激素治疗,观察两组稳定期时间、SLE临床表现、24h尿蛋白定量、系统性红斑狼疮疾病活动指数(SLEDAI)积分及补体C3等。结果治疗5年后两组症状(关节炎、浆膜炎、发热)组间比较差异有统计学意义(P<0.05)。第5年稳定期时间(天)治疗组(305.41±14.32)大于对照组(190.22±15.43);SLEDAI积分治疗组(8.28±4.12)低于对照组(12.79±5.43);24h尿蛋白(g/24h)治疗组(0.18±0.01)低于对照组(0.31±0.06);补体C3(g/L)治疗组(0.98±0.35)高于对照组(0.73±0.34);以上各指标治疗组改善优于对照组,差异皆有统计学意义(P<0.05)。不良反应发生治疗组15例,对照组62例,两组比较差异有统计学意义(P<0.05)。结论中西医结合治疗可减少脏器损害,延长SLE稳定期的持续时间,体现了治未病的思想。
Objective To investigate the long-term efficacy of integrative medicine in treating systemic lupus erythematosus(SLE).MethodsAdopting randomized grouping method,the SLE patients were assigned to two groups,74 in each group,the treatment group treated by combined hormonotherapy with Chinese drugs for detoxifying,and the control group treated by hormonotherapy alone.The period of the stable phase and active phase,clinical manifestations,24-h urinary protein,systemic lupus erythematosus disease activity index(...
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2009年第3期219-221,共3页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
系统性红斑狼疮
中西医结合
远期疗效
systemic lupus erythematosus
integrative TCM and Western medicine
long-term therapeutic efficacy
