SPSS 16.0在有机合成工艺优化中的应用

The application of SPSS 16.0 to the technological optimization of organic synthesis

以优化合成2-巯基苯并噻唑工艺条件为例,详细介绍使用SPSS16.0软件设计有机合成试验和试验数据统计分析法。根据试验因素水平,SPSS16.0可生成试验安排表,通过调整可以得到标准的正交试验安排表;将正交试验的结果输入调整后的正交试验中,分析并可得到正交试验方差表和单因素统计表,从而得到试验的优化条件。通过比较发现,SPSS16.0软件使用方便快捷,计算精确,结论可靠,并能避免大量人工计算。因此,SPSS16.0软件值得在有机合成工艺优化中推广。

The methods of designing organic synthesis experiment and analyzing experimental data by SPSS16.0 were introduced in detail with the example of the technological optimization of synthesizing 2-mercaptobenzothiazole.According to factors and levels, SPSS16.0 gires test table,a normative orthogonal test table is got by adjustment,test results are inputted to the table and analyzed,analysis of variance and statistics of single factor are got,and optimization conditions can be got.By comparison,it is found that ...