螺旋CT对日本大耳白兔气道的测量研究

Measuring of the airway dimensions with spiral CT images: an experimental study in Japanese white big-ear rabbits

目的探讨日本大耳白兔气管和主支气管各解剖径线的长度、角度及相关性,为进行气道疾病内支架介入治疗的动物实验研究奠定基础。方法用多层螺旋CT扫描30只成年健康日本大耳白兔的颈胸部,测量和测算气管各段前后径、左右径,声门水平到隆突的气管长度,左右主支气管和中间支气管内径与长度,以及左、右主支气管长轴与矢状面的夹角。结果气管各段直径、左右上肺尖叶支气管开口内径无差异,右主支气管长度、右主支气管长轴与矢状面夹角小于左侧,右主支气管内径大于左侧并有相关性。结论多层螺旋CT测定的日本大耳白兔气管、左和右主支气管径线值,获得左、右主支气管内径值、长度、嵴下角之间的回归方程,有助于为兔实验提供相关气管和支气管的解剖参数。

Objective To measure the length, angle and their correlation of the main anatomical dimensions of the trachea and bronchus in experimental Japanese white big-ear rabbits with the help of spiral CT 3D images, in order to lay the foundation of treating the airway disorders with stenting in animal experiment. Methods Multi-slice CT scanning of cervico-thoracic region was performed in 30 healthy adult Japanese white big-ear rabbits, the longitudinal, transversal dimensions of the trachea, the glottis-carina length, the inner diameter and length of bronchi, and the angle formed by bronchial long axis and sagittal section were measured. Results No significant difference was found in the inner diameters of various parts of the trachea and upper apical bronchi. The angle formed by bronchial long axis and sagittal section were smaller than that of the left ones. And the inner diameters of the right main bronchus was bigger than the left ones. Conclusion The complex branching structure of the rabbit airway tree can be well displayed on spiral CT 3D images. Through measuring and statistical analysis of the results the authors have got a regressive equation for estimating the value of the inner diameter, length, angle, etc. concerning the airway tree, which is very helpful for providing the useful anatomical parameters in rabbit experiment.