脑电双频指数监测对全麻诱导丙泊酚用量的指导价值

Significance of bispectral index monitoring in selecting the dose of propofol for induction of general anesthesia

目的探讨脑电双频指数(BIS)监测在老年患者选择丙泊酚诱导用量的指导价值。方法全麻老年患者40例,年龄65～75岁,ASAⅠ或Ⅱ级,随机分为两组。A组在BIS监测下缓慢推注丙泊酚,使BIS值降至40～50时停止;B组根据经验使用丙泊酚1.5～2 mg/kg。两组均复合维库溴胺0.1 mg/kg,芬太尼3μg/kg后行气管插管。连续监测围诱导期的血压(BP)、心率(HR)和BIS;记录丙泊酚的用量和BIS值。结果A组诱导用丙泊酚总量平均(1.33±0.50)mg/kg,明显少于B组的(1.62±0.70)mg/kg(P<0.05);B组BP和BIS值均明显降低于A组(P<0.05)。结论BIS监测能指导临床选择合适的丙泊酚诱导用量;在老年全麻患者,诱导用丙泊酚(1.33±0.5)mg/kg,既能取得足够的麻醉深度,又能维持较稳定的血流动力学状态。

Objective To study the significance of bispectral index(BIS) monitoring in selecting the dose of propofol for induction of general anesthesia in the elderly.Methods Forty patients,aged 65 to 75 years old and ASA class Ⅰ or Ⅱ,were randomly divided into two groups.The patients in group A were given intravenous injection of propofol at the dose of making BIS of 40～50,while those in group B were given propofol at the dose of 1.5～2.0 mg/kg.All patients received BIS monitoring and intubation after fentanyl 3 μk/k...