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血清微小RNA在肿瘤中的标志作用

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摘要 动植物中广泛存在着一类非编码小分子RNA,长度大约为20~25个核苷酸,它们被名为微小RNA(micro RNA)。研究表明micro RNA在肿瘤发生发展过程中,具有与癌基因或抑癌基因相似的作用,因此,micro RNA可能成为肿瘤治疗、预后和判定疗效的生物学标记,这有可能改变以往有创伤且昂贵繁杂的肿瘤标记物检测。本文综述血清micro RNA的基础研究、检测手段以其作为标志物在临床的应用。
作者 高雯 束永前
出处 《江苏医药》 CAS CSCD 北大核心 2009年第2期222-224,共3页 Jiangsu Medical Journal
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