绿激光光汽化术治疗晚期前列腺癌伴膀胱出口梗阻

The treatment of advanced prostate cancer with bladder outlet obstruction with photoselective vaporization of the prostate

目的比较前列腺绿激光光汽化术与经尿道前列腺电切术治疗晚期前列腺癌伴膀胱出口梗阻的安全性及有效性。方法40例晚期前列腺癌伴有膀胱出口梗阻的患者随机分成激光组和电切组,分别采用绿激光光汽化术和电切术进行姑息性治疗,并同时联合药物去势加雄激素受体阻断的间歇性治疗方案,随访6～96个月。结果激光组术中术后出血、导尿管留置时间、住院天数、手术并发症均明显低于电切组(P<0.05);两组术后1个月国际前列腺症状评分(IPSS)、最大尿流率(Qmax)和残余尿量(PVR)与术前相比均有明显改善(P<0.01)。结论与电切术相比,绿激光光汽化术治疗晚期前列腺癌具有创伤小、出血少、恢复快,并能够有效减少手术并发症。

Objective To evaluate the effect and safety of photoselective vaporization of the prostate(PVP) for the treatment of advanced prostate cancer with bladder outlet obstruction.Methods Fourty cases of advanced prostate cancer with bladder outlet obstruction were divided randomly into laser group and resection group treated by PVP and transurethral resection of the prostate(TURP),respectively.The therapy was combined with drugs castration and androgen receptor antagonist for appeasement therapy.The outcomes wer...