BNP在诊断心衰中的干扰因素探讨

Discussion of factors of interference on diagnosis of heart failure by BNP

BNP(B型钠尿肽)作为心力衰竭标示物越来越被人们认可。最新欧洲心脏病协会提出的心力衰竭指南,将血浆BNP水平作为一个心力衰竭诊断客观指标;美国FDA要求所有急诊室对怀疑的心衰患者必须做血浆BNP水平的测定。但在临床上,由于患者病情复杂,BNP的升高是否可诊断心衰,同认识肌钙蛋白与心肌梗死之间关系一样,需要深刻了解BNP在临床诊断心衰中的干扰因素。

BNP(B-type natriuretic peptide) as a marker of heart failure is increasingly being recognized.The heart failure guide of European Heart Association puts the plasma BNP levels as a objective indicator for heart failure.In U.S.A,FDA requires that all patients in emergency room with suspected heart failure should take the test of plasma BNP levels.However,the condition of patients in the clinical is too complex,and whether the rise of BNP level can diagnose heart failure is uncertain.We need to gain a profound...