摘要
目的:探讨生精散胶囊对小鼠生殖能力改善的作用机制。方法:对比肾阳虚小鼠使用生精散胶囊治疗前后其生殖激素水平及SOD、MDA的变化。结果:肾阳虚小鼠灌胃生精散胶囊治疗后血FSH、LH、T、GnRH均明显升高(P<0.05),小鼠附睾组织匀浆MDA浓度明显降低,而SOD浓度显著升高(P<0.05)。结论:生精散通过调节垂体-下丘脑-性腺轴的功能来调节生精过程,并且可增强体内抗氧化酶活性,增强附睾功能,从而发挥抗氧化作用,保护附睾精子免受氧化损伤。
Objective: To explore the mechanism of Sheng Jing San capsule to improve the reproductive ability of mice.Method: To compare the reproductive hormone levels and SOD,MDA in mice with deficiency of Kidney Yang before and after use the Sheng Jing San capsule.Results: The Sheng Jing San capsule group comparing to the model group as follow: the containment of GnRH,LH,FSH,and T in the blood become higher(P<0.05),containment of MDA in the epididymis tissue was lower,and concentration of SOD increased(P<0.05)...
出处
《辽宁中医药大学学报》
CAS
2009年第4期200-201,共2页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
肾阳虚
生精散
生殖激素
抗氧化作用
deficiency of kidney yang
Sheng Jing San capsule
reproductive hormone
antioxidant
