中药广藿香非挥发性化学成分的研究

Chemical constituents from involatile moiety of Pogostemon cablin

目的:研究广藿香非挥发性部位的化学成分。方法:采用多种色谱技术分离纯化化合物,根据化合物的理化性质和波谱数据鉴定其结构。结果:从中药广藿香全草95%乙醇提取物的醋酸乙酯萃取部分分离得到9个化合物,分别鉴定为:表木栓醇(1),5-羟甲基糠醛(2),1,4-丁二酸(3),β-谷甾醇(4),胡萝卜苷(5),1,2-O-[2S-(3,4-二羟基苯基)-l,2-乙烷二基]-3-O-α-L-鼠李毗喃糖基-4-O-咖啡酰基-β-D-葡萄毗喃糖苷(6)、1,2-O-[2S-(3,4-二羟基苯基)-l,2-乙烷二基]-3-O-α-L-鼠李毗喃糖基-4-O-阿魏酰基-β-D-葡萄毗喃糖苷(7)、1,2-O-[2S-(3,4-二羟基苯基)-l,2-乙烷二基]-3-O-α-L-鼠李毗喃糖基-6-O-咖啡酰基-β-D-葡萄毗喃糖苷(8)和芹菜素-7-O-β-D-(6″-对位香豆酰基)-葡萄糖苷(9)。结论:化合物2,3,6～8均为首次从该属植物中分离得到。

Objective:To study the chemical constituents of involatile moiety of Pogostemon cablin.Method:Compounds were isolated and purified by repeated column chromatography,and their structures were elucidated by spectroscopic analysis.Result:Nine compounds have been isolated and identified:epifriedelinol(1),5-hydroxymethol-2-furfural(2),succinic acid(3),β-sitosterol(4),daucosterol(5),crenatoside(6),3 ″-O-methylcrenatoside(7),isocrenatoside(8),and apigenin-7-O-β-D-(6″-p-coumaryl)-glucoside(9).Conclusion:Compounds 2...