朝天罐根化学成分的研究(英文)

Chemical constituents in roots of Osbeckia opipara

目的:研究朝天罐Osbeckia opipara根化学成分。方法:通过多种柱色谱方法进行分离纯化,根据化合物的理化性质和光谱数据进行结构鉴定。结果:从朝天罐根的甲醇提取物中分离得到12个化合物:lasiodiplodin(1),de-O-methyllasiodiplodin(2),2,3-dihydro-2-hydroxy-2,4-dimethyl-5-trans-propenylfuran-3-one(3),integracin(4),5α,8α-epidioxy-(22E,24R)-ergosta-6,22-dien-3β-ol(5),3,3',4'-tri-O-methylellagicacid(6),5-羟甲基糠醛(7),吐叶醇(8),白桦脂酸(9),2α-羟基乌索酸(10),(24R)-Stigmast-4-ene-3-one(11),eugenitin(12)。结论:所有化合物均为首次从该植物中分离得到。

Objective:To study the chemical constituents of the roots of Osbeckia opipara.Method:Repeated column chromatography over silica gel,RP-18 and Sephadex LH-20,and preparative thin layer chromatography(PTLC)were used to isolate the compounds,whose structures were determined by spectroscopic methods by direct comparing spectral data with those reported references.Result:From the MeOH extract of the roots O.opipara,twelve compounds were isolated and identified as follows:lasiodiplodin(1),de-O-methyllasiodiplodin...