东方肉穗草黄酮类化学成分研究

Flavonoid constituents from herbs of Sarcopyramis bodinieri var. delicata

目的:系统研究东方肉穗草中的黄酮类化学成分。方法:利用大孔吸附树脂、Sephadex LH-20,ODS及正相硅胶柱等色谱手段进行分离,通过多种波谱学数据分析进行黄酮类化合物的结构鉴定。结果:从醋酸乙酯部分分离得到8个黄酮类化合物,经鉴定为异鼠李素(1)、槲皮素(2)、异鼠李素-3-O-β-D-吡喃葡萄糖苷(3)、槲皮素-3-O-β-D-葡萄糖苷(4)、异鼠李素-3-D-(6″-乙酰基)-β-D-吡喃葡萄糖苷(5)、异鼠李素-3-O-(2″-乙酰基)-β-D-吡喃葡萄糖苷(6)、槲皮素-3-O- (6″-乙酰基)-β-D-吡喃葡萄糖苷(7)、槲皮素-3-O-(6″-反式-对香豆酰基)-β-D-吡喃葡萄糖苷(8)。结论:所有化合物均系首次从该属植物中分离鉴定。

Phytochemical studies of the the herb Sarcopyramis bodinieri var.delicate (Melastomataceae) have been carded out.The compounds were separated by repeated D101 macroporous adsorption resin column combined with Sephadex LH-20,ODS, and silica gel chromatgrophy.The structures were identified on the basis of extensive spectroscopic data analysis,and by comparison of their spectral data with those reported.Eight flavonoid compounds isolated from the ethyl acetate extract was identified as isorhamnetin (1),quercet...