天山花楸醋酸乙酯部位化学成分研究

Studies on chemical constituents from EtOAc fraction of Sorbus tianschanica

目的:研究天山花楸的化学成分,为进一步拓展天山花楸的药理功效,开发利用天山花楸奠定基础。方法:利用硅胶、树脂柱色谱等手段进行分离,结合现代波谱技术(~1H-NMR,^(13)C-NMR,IR等)及现代分析方法鉴定化合物的结构。结果:从天山花楸乙醇提取浸膏中分离得到6个化合物,鉴定为苯甲酸(benzoic acid,1),苄基-O-β-D吡喃葡萄糖苷(benzvl-O-β-D-glucopyranoside,2),乌苏酸(ursolic acid,3),2α-羟基乌苏酸(2α-hydroxyursolic acid,4),金丝桃苷(hyperoside,5),槲皮素-3-O-葡萄糖苷(quercetin-3-O-glucoside,6)。结论:化合物1～5为首次从天山花楸中得到。

Objective:To study the chemical constituents of Sorbus tianschanica.Method:The compounds were isolated and purified by recrystallization and chromatography with silica gel and resin.Their structures were identified by physicochemical properties and spectral analysis.Result.Seven compounds were isolated from the EtOH extraction and six structures were identified as benzoic acid (1),benzyl-O-β-D-glucopyranoside (2),ursolic acid (3),2α-hydroxyursolic acid (4),hyperoside (5), quereetin-3-O-glucoside (6).Conclus...