经颈动脉与肘静脉联合注射小剂量尿激酶治疗急性脑梗死近期疗效观察

Curative effect of low dose UK infection through arteria carotis and ulnar vein in the patients of acute cerebral infarction in the near future

目的:探讨小剂量尿激酶颈动脉推注和尿激酶静脉联合溶栓治疗与单纯大剂量尿激酶静脉溶栓治疗对发病9小时内颈内动脉系统脑梗死患者的疗效。方法:A组对44例脑梗死患者应用尿激酶20万u颈动脉推注溶栓,继之静点50万u尿激酶;B组对44例脑梗死患者应用尿激酶150u静滴溶栓治疗。结果:基本治愈率;治疗2小时A组9例(20.5%),B组0例(0%);治疗1日A组14例(31.8%),B组3例(6.8%);治疗7日A组29例(65.9%),B组12例(27.3%);治疗14日29例(65.9%),B组17例(38.6%)。两组比较有显著性差异(P<0.05)。A组中所有病例均无明显出血倾向;B组有6例(13.6%)患者有不同程度的出血。结论:发病9小时内颈内动脉系统脑梗死患者尿激酶动静脉联合溶栓与静脉溶栓疗效均较高,而基本治愈率A组明显优于B组。

Objective:Compared the curative effect of combined thrombolysis(push the urokinase(UK)into the carotid artery system lose dose and intravenous injection of UK)and simple thrombolysis(intravenous transfusion of UK high dose)in the patients of cerebral infarction of carotid artery system within 9 hours.Methods:Group A:Push UK 20 ten thousand unit into the carotid artery and then intravenous injection of 50 ten thousand unit UK into the 44 patients.Group B:Intravenous injection of 150 ten thousand unit UK into...