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ESRD患者颈动脉内中膜增厚及其可能影响因素分析 被引量:3

The Increasing Carotid Intima-media Thickness and the Possible Risk Factors in Patients with End-stage Renal Disease
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摘要 目的比较终末期肾脏病(end-stage renal disease,ESRD)患者维持性血液透析者(maintenance hemodialysis,MHD)和非血液透析者颈动脉内中膜增厚程度的不同,探讨影响终末期肾脏病患者动脉粥样硬化(atherosclerosis,AS)发生发展的可能因素。方法选择病情稳定的MHD患者45例;慢性肾脏病4~5期未透析(chronic kidney disease not subjected to hemodialysis,CKD-non-HD)患者23例;健康对照组20例。采用高分辨率超声测定颈总动脉(common carotid arteries,CCA)、颈动脉分叉处(thebifurcation of carotid arteries,CB)及颈内动脉起始段(internal carotid arteries,CI)内中膜厚度(intima-media thickness,IMT)。结果MHD和CKD-non-HD患者CCA-IMT、CB-IMT及CI-IMT均较对照组高(P均<0.05)。但MHD组和CKD-non-HD组之间CCA-IMT、CB-IMT及CI-... Objective The aim of our study is to find out whether atherosclerosis of dialysis patients is effectively accelerated due to the fact that many such patients at the start of dialysis treatment.Methods Using B-mode ultrasonography,we conducted a cross-sectional study to compare intima-media thickness in the common carotid arteries(CC),in the area of bifurcation(CB)and in the proximal part of internal carotid arteries(CI)for 45 MHD patients,of which 23 patients had chronic kidney diseases not subjected to hem...
出处 《首都医科大学学报》 CAS 北大核心 2009年第2期126-129,共4页 Journal of Capital Medical University
基金 北京西城区科技计划(2008018)资助项目~~
关键词 终末期肾脏病 动脉粥样硬化 内中膜厚度 end-stage renal disease atherosclerosis intima-media thickness
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参考文献10

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同被引文献38

  • 1陈婷,陈孝文,唐德燊,梁东,刘华锋.尿毒症患者血清白细胞介素-18水平与脂代谢紊乱的关系[J].临床内科杂志,2004,21(7):465-467. 被引量:3
  • 2武强,刘郑荣,侯凡凡,刘尚喜,刘俊,杨小兵,田建伟,任昊,蒋建平.维生素E对血液透析病人氧化应激的干预效果[J].解放军医学杂志,2004,29(11):955-957. 被引量:6
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  • 6Hiroshiyamagami, Kazuo Kitagawa, Taku Hoshi, et al. Associations of serum IL-18 levels with carotid intima-media thickness [ J ]. Ar- terioscler Throdo Vasc Biol,2005,25 : 1458 - 1462.
  • 7Peter S. Inflammation in end-stage renal failure:could it be trea- ted [ J ]. Nephrol Dial Transplant, 2002,17 ( suppll 8 ) :33 - 38.
  • 8Acarturk E, Koc M, Bozkurt A, et al. Left atrial size may pre- dict exercise capacity and cardiovascular events in patients with heart failure. Tex Heart Inst J, 2008,35(2):136-143.
  • 9Meris A, Amigom M, Uno H, et al. Left atrial remodeling in pa- tients with myocardial infarction complicated by heart failure left ventricular dysfunction or both the VALIANT Echo study. Eur Heart J, 2009,30(1) :56-65.
  • 10Kocinaj D, Gshi M, Berisha M, et al. Echocardiogrphic assess- ment of left atrial size in patients with end stage renal disease. Cardiovasc J Afr, 2009,20(3) :183-186.

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