老年慢性肾脏病并发急性肾损伤的危险因素分析

Risk Factors of Complicated Acute Kidney Injury in Elderly Patients with Chronic Nephropathy

目的探讨老年慢性肾脏病并发急性肾损伤的危险因素。方法回顾性分析我院2001—2007年收治的92例慢性肾脏病并发急性肾损伤患者的临床资料,按年龄将其分为老年组(≥60岁,n=48)和中青年组(<60岁,n=44),分析两组患者的临床资料、治疗及转归。结果在导致老年患者急性肾损伤的危险因素中,以严重感染(29.17%)、肾毒性药物(22.92%)、低血容量(16.67%)等为主要原因,与中青年组比较差异有统计学意义(P<0.05),老年组治疗总有效率与中青年组比较差异有统计学意义(P<0.05)。结论老年慢性肾脏病患者并发急性肾损伤的危险因素较多,重视急性肾损伤发生的高危因素并及早发现,及时控制各种感染,避免使用肾毒性药物,加强原发病的整体治疗,对于急性肾损伤的预防具有十分重要意义。

Objective To investigate the risk factors of the acute kidney injury secondary to chronic nephropathy in the elderly patients.Methods Retrospective analysis was conducted for the clinical data of 92 patients with chronic nephropathy complicated by acute kidney injury in our hospital from January 2001 to December 2007.They were divided as group A in which 48 elderly patients whose ages were above 60,and group B in which 44 middle-aged and young patients whose ages were under 60.The clinical data,treatments a...