脑梗死后抑郁与病灶部位和面积的相关性研究

Correlation between Post-infarction Depression and Focal Location and Area of Cerebral Infarction

目的研究脑梗死患者急性期抑郁状态与病灶部位和面积的关系。方法选取初发急性脑梗死患者180例,根据汉密顿抑郁量表(HAMD)评分结果分为伴抑郁组和无抑郁组,分析脑梗死后抑郁与梗死病灶部位和面积的关系。结果(1)两组患者左侧大脑半球梗死率间差异有统计学意义(P<0.05);(2)两组患者小脑脑干梗死率、双侧大脑多发性梗死率间差异无统计学意义(P>0.05);(3)伴抑郁脑梗死患者中病灶最大直径≥3.6cm者39例,占43.3%,无抑郁脑梗死患者中病灶最大直径≥3.6cm者26例,占28.9%;(4)伴抑郁脑梗死患者中,病灶直径≥3.6cm的患者中、重度抑郁26例,占66.7%(26/39),病灶直径<3.6cm的患者中,重度抑郁9例,占17.6%(9/51),二者比较差异有统计学意义(P<0.01)。结论脑梗死患者抑郁状态与病灶位于左侧半球有关,且与病灶面积呈相关性。

Objective To study the relation between depression at acute stage and focal location and area in patients with cerebral infarction.Methods One hundreds and eighty patients with a diagnosis of first ever cerebral infarct were included in the study and were divided into depression group and non-depression group according to Hamilton depression rating scale(HAMD).The conditions of infarction location and area between the two groups were compared.Results Between the two groups,there were significant differences...