摘要
目的了解肾病综合征(NS)并喘息性疾病的临床特点,评估其易患喘息性疾病的高危因素。方法收集1998年1月-2007年9月在本院儿科住院的NS并喘息性疾病142例;对其临床资料进行回顾性分析。结果1.NS并喘息性疾病者占同期住院NS患儿总数的12.49%;并哮喘者占NS总病例的1.06%。2.NS并喘息性疾病66.2%的病例发生于春夏季节;发病年龄中位数为3.6岁;13.38%的病例存在既往过敏史,7.75%的病例有既往毛细支气管炎病史;89.4%病例喘息发生于NS使用足量激素时。2.NS患儿易患喘息性疾病的高危因素包括年龄较小(OR=10.754),春夏季节(OR=1.545),既往过敏性疾病史(OR=5.722),毛细支气管炎病史(OR=13.490),治疗前血清蛋白较低(OR=3.864),治疗前尿蛋白定量较高(OR=1.166)。结论NS并喘息性疾病好发于春夏;发病年龄较小,既往过敏性疾病史、治疗前血清蛋白较低、尿蛋白定量较高为NS患儿易患喘息性疾病的高危因素。
Objective To explore the clinical characteristics of nephrotic syndrome(NS) complicated with wheezing diseases,and to evaluate high risk factors contributing to wheezing diseases in NS children.Methods One hundred and forty-two children of NS complated with wheezing diseases were selected from Jan.1998 to Sep.2007 in the First Affiliated Hospital of Sun Yat-Sen University.And the data of the 142 cases were analyzed.Results 1.The incidence of wheezing diseases in NS children in our hospital was 12.49%,the in...
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2009年第9期674-676,共3页
Journal of Applied Clinical Pediatrics
关键词
肾病综合征
喘息性疾病
高危因素
nephrotic syndrome
wheezing diseases
high risk factors
