大黄不同给药途径治疗危重病患者胃肠功能障碍的临床观察

Clinic Effect of Rhubarb by Different Administration Route in Critical Patients with Gastrointestinal Dysfunction

目的观察大黄不同的给药途径对危重病患者胃肠功能障碍的治疗作用。方法选择148例并发胃肠功能障碍的危重病患者,并将患者按用药途径分为3组:胃内注入组、高位灌肠组和联合治疗组。3组患者均给予常规综合治疗(制酸、止血、胃引流),此外,胃内注入组患者还给予大黄胃管注入,高位灌肠组患者给予大黄高位灌肠,联合治疗组患者给予大黄经胃管注入联合高位灌肠。比较3组患者治疗后在胃肠出血、胃引流及肠麻痹方面的治疗效果。结果联合治疗组患者在胃肠道出血、胃引流、肠麻痹方面的有效率(分别为84.2%、80.7%和82.4%)与胃内注入组(分别为60.4%、52.1%和58.3%)、高位灌肠组(分别为58.1%、55.8%和55.8%)比较,差异均有统计学意义(P<0.05);且联合治疗组患者开始耐受肠内营养的时间〔(3.6±2.4)d〕与其他两组〔分别为(5.5±2.2)d和(5.8±3.7)d〕比较,差异亦有统计学意义(P<0.01)。结论大黄胃管内注入联合高位灌肠治疗对危重病患者的胃肠功能障碍具有较好的治疗效果,且能缩短开始耐受肠内营养的时间。

Objective To observe the therapeutic effect of rhubarb by different administration route on the critical patients with gastrointestinal dysfunction.Methods Totally 138 critical patients with complication of gastrointestinal dysfunction were divided into 3 groups:gastric tube group,high enema group and combination group.All the patients were treated with conventional treatment of acid inhibition,hemostasis and stomach drainage.Besides,the patients were treated with rhubarb through gastric tube in the gastric...