经皮穿刺臭氧治疗椎间盘突出症的实验和临床研究进展

Progress in Experiments and Clinical Research of Ozone by Percutaneous Puncture in Dorsal Disc Prolapse

臭氧能通过氧化蛋白多糖发挥降低髓核渗透压、减轻炎症反应及镇痛等作用,从而达到治疗椎间盘突出症的效果。将其与经皮椎间盘切除术、神经根周围注射类固醇术、经皮腰椎间盘切吸术等对比,发现臭氧治疗椎间盘突出症安全、有效;臭氧注射与胶原酶或离子射频联合可以提高治疗效果。正确评估椎间盘突出及椎管狭窄情况,严格掌握适应证及禁忌证是提高疗效的关键。本文就经皮穿刺臭氧治疗椎间盘突出症的研究进展进行综述。

Ozone can reduce nucleus pulposus osmotic pressure and inflammatory reaction and relieve pains by oxidating proteoglycans,thus to achieve the goal of treating dorsal disc prolapse.Ozone therapy is found more safe and effective in treatment of dorsal disc prolapse when comparing it with percutaneous diskectomy,nerve root injection of steroids and so on.Ozone injection with collagenase or with ion radio frequency can improve therapeutic effect.It is the key of improving treatment to assess correctly the statu...