蔓生百部中新生物碱的结构研究

Studies on New Alkaloids of Stemona Japonica Miq

研究蔓生百部中微量生物碱的结构。方法 :减压柱层析、波谱分析和化学转化。结果 :得到 3种微量生物碱 ,分别为脱氢百部碱、百部碱、原百部碱。结论 :其中脱氢百部碱为一新生物碱 ,原百部碱是首次从蔓生百部中得到 ;

Objective To study the alkaloid structures of stemona japonica Miq.Methods Some stemona alkaloids were isolated by reduced pressure chromatography.Their structures were identified by various spectral analysis (IR、MS, 1HNMR, 13 CNMR, 1H- 1HCOSY,NOESY) as well as chemical reaction.Results Three stemona alkaloids,named didehydrostemonine,stemonine,didehydroprotostemonine were isolated.Conclusion Didehydrostemonine is a new alkaloid and the didehydroprotostemonine isolated from the roots of s. Japonica i...