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OPTIMAL FEED STRATEGY FOR FED-BATCH GLYCEROL FERMENTATION DETERMINED BY MAXIMUM PRINCIPLE

OPTIMAL FEED STRATEGY FOR FED-BATCH GLYCEROL FERMENTATION DETERMINED BY MAXIMUM PRINCIPLE
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摘要 Optimal glucose feed strategy for glycerol fed-batch fermentation was investigated by Pontryagin’s maximum principle to maximize the final glycerol yield. The problem was solved by a nonsingular control approach by selecting the culture volume as the control variable, then the general optimal feed profile was numerically determined. Optimal glucose feed strategy for glycerol fed-batch fermentation was investigated by Pontryagin s maximum principle to maximize the final glycerol yield. The problem was solved by a nonsingular control approach by selecting the culture volume as the control variable, then the general optimal feed profile was numerically determined.
出处 《化工学报》 EI CAS CSCD 北大核心 2000年第S1期236-239,共4页 CIESC Journal
基金 From National Ninth Five Years Project (NO. 96-03-03-03A).
关键词 Optimal feed strategy GLYCEROL FERMENTATION Maximum principle Optimal feed strategy Glycerol Fermentation Maximum principle
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参考文献1

  • 1J.-H. Lee,H. C. Lim,Y. J. Yoo,Y. H. Park.Optimization of feed rate profile for the monoclonal antibody production[J].Bioprocess Engineering.1999(2)

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