期刊文献+

补体攻膜复合物细胞非致死性效应及其信号转导机制 被引量:2

The non-lethal effects of complement membrane attack complex and its signal transduction mechanism
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摘要 有核细胞能通过自身机制抵抗同源补体溶破 ,同时亚溶破 MAC在细胞膜上沉积后 ,能刺激多种细胞的多种生物学活性改变 ,包括产生活性氧、释放花生四烯酸及其代谢产物、产生多种细胞因子、诱导膜蛋白表达和诱导细胞进入细胞周期等 ,此称 MAC的细胞非致死效应。这些效应是由 MAC活化细胞跨膜信号转导机制介导的。
出处 《免疫学杂志》 CAS CSCD 北大核心 2000年第z1期1-4,共4页 Immunological Journal
基金 国家自然科学基金!资助项目 (39770 16 3)
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参考文献24

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同被引文献34

  • 1佟建霞 ,王迎伟 .亚溶解型补体C5b-9复合物与细胞内信号转导通路[J].国外医学(免疫学分册),2005,28(6):376-380. 被引量:3
  • 2张云,上官毕文.妊高征患者产前产后血浆SC5b-9的变化及其意义[J].中国妇幼保健,2006,21(22):3153-3153. 被引量:1
  • 3王金泉.膜攻击复合物与肾脏疾病[J].国外医学(泌尿系统分册),1996,16(5):228-232. 被引量:1
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