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CD59的结构与功能关系研究进展 被引量:6

Progress of the study on the structure-function relationship of CD59
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摘要 CD5 9是一种 GPI锚型的补体调节蛋白 ,它是一个多功能的分子 ,其主要作用是与新生补体攻膜复合物中的C8和 /或 C9结合从而抑制补体的活化。了解 CD5 9的结构与功能关系可为提高抗肿瘤抗体的治疗效果、治疗自身免疫和炎症性疾病及抑制器官移植的超急性排斥反应奠定基础。本文就近年来 CD5 9的结构与功能关系的研究进展作一综述。
作者 杜瑞琴 白云
出处 《免疫学杂志》 CAS CSCD 北大核心 2000年第z1期18-23,共6页 Immunological Journal
基金 国家自然科学基金!资助项目 (396 30 2 90 38)
关键词 CD59 结构 功能
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参考文献21

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