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胃肠道非霍奇金淋巴瘤的核形态定量分析

AN ANALYSIS OF MORPHOMETRY ON GANSTROTNTESTINAL NON -HODGKING' LYMPHOMA
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摘要 应用图像分析手段对胃肠道31例非霍奇金淋巴瘤(NHL)进行了细胞核形态定量研究。结果显示:Kiel分类低度恶性组与高度恶性组的核形态定量的主要参数(核面积、核等效直径、核最长径和形状因子)均有高度显著性差异(P<0.01);WF分类低度恶性组、中度恶性组与高度恶性组之间的核形态定量参数比较,大多数核形态定量分析与形态分类在胃肠道NHL的恶性程度的评判上基本吻合。 It was determined the morphometric parameters of cell nuclei of 31 patients with gas-trointesinal non - Hodgking's lymphoma by means of automatic image analysis system. The results showed that the major morphometric parameters of these cell nuclei (area, mean diameter, maximal di-amter, shape factor) were significantly different between low -garde malignant group and high -garde malignant group by Kiel classification (P<0. 01). Based on working formulation, most of these parameters were also significantly different among low - grade, middle - grade and high - grade malignant group(P<0. 01-0. 05). It is indicated that both morphometry on cell nuclei and these two morphological classification are very corresponding indetermining the malignant grade of gastrointestinal non -Hodgking's lymphoma.
出处 《西南国防医药》 CAS 2000年第4期196-198,共3页 Medical Journal of National Defending Forces in Southwest China
关键词 胃肠道 淋巴瘤 图像分析 gastrointestine lymphoma tumor morphology image analyisi
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参考文献5

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  • 5蔡瑞霞,张惠箴,周健华,陈洁晴.62例原发性胃肠道恶性淋巴瘤病理新分类形态研究[J].临床与实验病理学杂志,1999,15(1):5-7. 被引量:14

二级参考文献3

  • 1王懿龄,实用外科病理学,1997年,372页
  • 2纪小龙,淋巴组织增生性疾病病理学,1994年,145页
  • 3李甘地,中华病理学杂志,1992年,21卷,135页

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