摘要
目的:探讨古方温清饮(WQY)的抗溃疡作用机理。方法:采用束缚-水浸应激溃疡大鼠模型,观察WQY对应激性溃疡大鼠血清MDA含量和SOD活性的影响。结果:WQY能降低应激性溃疡大鼠血清MDA的含量(P<0.01),增强SOD活性(P<0.05)。结论:WQY的抑制大鼠应激性溃疡形成作用与其抗氧化作用有关。
Objective:To discuss the mechanism of ulcer-preventive effects of ancient prescription wenqingyin.Methods:Rats were divided into 6 groups,normal,model,western medicine and wenqingyin three dose groups,they all were given correspending medicine for 15 days.Then models were made by fetter-water immersion method,each group rats' serum MDA content and SOD activity were tested.Results: Wenqingyin three doses could obviously raise serum SOD activity of rats with stress ulcer of stomach, reduce serum MDA content.Conclusion: Alleviating the gastric mucosa injury induced by free radical was one of the mechanism that wenqingyin inhibiting the formation of stress gastric ulcer.
出处
《中国中医药科技》
CAS
2009年第3期174-175,共2页
Chinese Journal of Traditional Medical Science and Technology
基金
黑龙江省科技攻关资助课题No.GC03C520-2
