压片木糖醇的研究

Review on the research of DC grade xylitol

木糖醇已被作为糖的替代品在某些领域(如口香糖)获得实际生产和商业上的成功。由于其味觉和生产工艺上的先进性,木糖醇的应用非常具有吸引力。木糖醇是一种天然的五碳糖醇,与蔗糖的甜度相当,但热量比较低。在许多水果和蔬菜中发现有少量木糖醇的存在。木糖醇在人体的自然代谢中也会产生。由于其在人体的代谢途径人们已经了解,并具有对口腔及技术性能上的一些特性,使木糖醇更具吸引力。但是木糖醇不能直接可压缩,即晶体木糖醇不能被直接压制成具有足够硬度和较低脆碎度的片剂。因此,为了在压片中应用木糖醇,人们尝试了很多方法来解决这种问题。本文描述了DC级木糖醇的研究进展情况。

Xylitol has been successfully used as a sugar substitute in certain areas(e.g.chewing gum)because of its taste and technological processing advantages.Xylitol is a natural five carbon sugar alcohol which has the same sweetness as sucrose but fewer calories.Xylitol is found at low content in many fruits and vegetables,and can be produced in the human body during normal metabolism.The application of Xylitol becomes hot due to the understanding of its metabolic process,cavity prevention and other characteristics.However,xylitol can not be compressible directly,the crystallized xylitol cannot be compressed into tablets due to its insufficient hardness and low friability.Therefore,in order to utilize xylitol in tablets,a variety of approaches have been studied.The paper described the advance research of DC(directly compressible)grade xylitol.