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不同血管活性药物对脓毒性休克血乳酸的影响 被引量:2

Effect of vasoactive drugs on concentration of lactic acid in patients with septic shock
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摘要 目的 观察去甲肾上腺索并多巴酚丁胺治疗脓毒性休克时血乳酸的变化.方法 我院ICU符合脓毒性休克的48例患者随机分为2组,A组给予去甲肾上腺素并多巴酚丁胺,B组给予大剂量多巴胺并多巴酚丁胺,观察治疗前及治疗后1 h、6 h、12 h、24 h动脉血乳酸浓度变化;记录休克治疗前、后24 h血pH、血乳酸、平均动脉压(MAP)、急性生理和慢性健康(APACHEII)评分的变化.结果 A组血pH、MAP显著高于B组,血乳酸、APACHEII评分显著低于B组.结论 在脓毒性休克的治疗中,在充分容量复苏的基础上给予去甲肾上腺素并多巴酚丁胺等血管活性药物,可以明显降低血乳酸浓度,改善微循环.
作者 冯敏 孙荣青
机构地区 [
出处 《中国心血管病研究》 CAS 2009年第7期518-520,共3页 Chinese Journal of Cardiovascular Research
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