膀胱占位性病变的超声造影特点及其诊断价值

Application of Contrast-enhanced Ultrasound in Diagnosis of Bladder Space-occupying Lesions

目的探讨膀胱占位性病变的超声造影特点及其诊断价值。方法对灰阶超声诊断为膀胱占位性病变的60例患者,同时采用超声造影检查,造影剂为声诺维,观察膀胱占位性病变组织和邻近膀胱壁组织中的造影剂到达时间(AT)、峰值时间(TTP)、峰值强度(PI)和廓清时间(DT)。结果膀胱占位性病变组织的AT、TTP、PI和DT分别为(18±5)s、(24±6)s、(33±8)dB和(31±7)s;邻近膀胱壁组织的AT、TTP、PI和DT分别为(23±6)s、(30±8)s、(18±7)dB和(23±5)s。两种组织中上述相应指标比较差别均有统计学意义(P<0.01)。超声造影诊断膀胱恶性肿瘤47例,良性肿瘤13例。与病理结果相比,有2例良性肿瘤被误诊为恶性肿瘤。结论与自身邻近膀胱壁组织的超声造影相比,膀胱恶性肿瘤组织的超声造影呈快增强、高增强、慢消退的特点,超声造影是无创诊断膀胱肿瘤的好方法。

Objective To explore the value of ultrasound contrast agent(CA) Sono Vue and Cadence Pulse sequencing(CPS)in diagnosing bladder space-occupying lesions(SOL).Methods Contrast-enhanced ultrasound examination was performed with Sono Vue CA in 60 WEI bladder SOL patients diagnosed by gray-scale ultrasound.The CA arrival time(AT),time to peak(TTP),peak intensity(PI) and clearance time in bladder SOL tissues and adjacent were observed.Results At,TTP,PI and clearance time were 18±5 s,24±6 s,33±8 dB,31±7 s,respectively,in bladder SOL tissues,and 23±6 s,30±8 s,18±7 dB,23±5 s,respectively,in adjacent tissues,the difference was significant(P<0.01).Forty-seven patients were diagnosed as bladder malignant tumor,13 as benign.Two benign were misdiagnosed as malignant tumor as compared with pathological results.Conclusion Contrast-enhanced ultrasound of bladder malignant tissues,characterized by rapid and high enhancement and slow regression as compared with that of adjacent tissues,is a good non-invasive method in diagnosing bladder neoplasms.