低分子肝素联合葛根素治疗不稳定型心绞痛疗效观察

Puerarin Low - Molecular - Weight Heparin Treatment of Unstable Angina Pectoris

[目的]观察低分子肝素(LMWH)联合葛根素注射液(PI)治疗不稳定型心绞痛的疗效及安全性。[方法]将82例不稳定型心绞痛患者随机分为两组:对照组41例,在常规治疗的基础上加用普通肝素维持静滴,连用5日;观察组41例,在常规治疗的基础上加用葛根素500mg静滴,1次/日,疗程14天,低分子肝素5000U皮下注射,1次/12h,连用5天。[结果]低分子肝素联合葛根素能有效缓解症状、改善心电图、心肌耗氧明显下降(P<0.05)。[结论]低分子肝素联合葛根素治疗不稳定型心绞痛有效、安全。

[Objective] To observe the low molecular weight heparin ( LMWH) combined puerarin injection (PI) treatment of unstable angina pectoris and security. [Methods]82 cases of unstable angina were randomly divided into two groups:control group, 41 cases of conventional therapy plus intravenous unfractionated heparin to maintain, once a 5 ; 41 cases of the observation group, in the conventional based on treatment with intravenous 500mg Puerarin 1 times / day, treatment for 14 days, subcutaneous low molecular weight heparin 5000U, 1 / 12h, once a 5 days. [Results? Puerarin low -molecular-weight heparin are effective to alleviate the symptoms and improve the electrocardiogram, myocardial oxygen consumption decreased significantly (P < 0.05). [ Conclusion] The low molecular weight heparin treatment of unstable angina Puerarin effective and safe.