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阿尔茨海默病患者血尿酸水平的检测及意义 被引量:13

Relationship between the Level of Serum Uric Acid and Alzheimer’s Disease
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摘要 目的探讨血尿酸水平与阿尔茨海默病(AD)的关系。方法检测30例AD患者和30例健康对照者的血尿酸水平。结果AD组血尿酸水平低于健康对照组,差异有统计学意义(P<0.01)。健康对照组男性的血尿酸水平明显高于女性(P<0.05),AD组男性的血尿酸水平与女性比较无统计学意义(P>0.05)。结论血尿酸水平降低可能与AD的发病机制有关。 Objective To assess the relationship between the level of serum uric acid and Alzheimer’s disease (AD). Methods Thirty patients with AD and 30 normal control subjects were included. The level of serum uric acid was measured. Results The level of serum uric acid in AD patients was significantly lower than that in normal control subjects(P < 0.05). The level of serum uric acid in male normal control subjects was significantly higher than that in female (P < 0.05). No significant difference in the level ...
出处 《中国医科大学学报》 CAS CSCD 北大核心 2009年第5期333-334,共2页 Journal of China Medical University
基金 国家自然科学基金青年基金资助项目(30700938) 辽宁省自然科学基金资助项目(20082078) 辽宁省教育厅科研基金资助项目(05L559)
关键词 血尿酸 阿尔茨海默病 serum uric acid Alzheimer’s disease
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  • 1Rui-Sheng Duan,Xin Yang,Zhi-Guo Chen,Ming-Ou Lu,Chris Morris,Bengt Winblad,Jie Zhu. Decreased Fractalkine and Increased IP-10 Expression in Aged Brain of APPswe Transgenic Mice[J] 2008,Neurochemical Research(6):1085~1089

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