舒芬太尼和芬太尼抑制双腔支气管插管心血管反应效果比较

A Comparison of Sufentanil and Fentanyl Releving Cardiovascular Response to Intubation with Double-lumen Tubes

目的比较舒芬太尼和芬太尼抑制双腔支气管插管心血管反应的效果。方法拟施行胸外科择期手术需双腔支气管插管患者60例,ASAⅠ-Ⅱ,随机分为2组:舒芬太尼组(SF组,0.3μg/kg,n=30)和芬太尼组(F组,3μg/kg,n=30)。分别记录2组麻醉诱导前(T0)、注药后插管前即刻(T1)、双腔支气管插管后即刻(T2)、插管后1 min(T3)、3 min(T4)和5 min(T5)各时点的收缩压(SBP)、舒张压(DBP)、心率(HR)值。结果2组患者T0时SBP、DBP、HR组间比较均无显著性差异(P>0.05)。诱导后2组患者各项指标与后时比较均显著降低(P<0.05)。插管后T2~T4各时点F组各指标与基础值比均明显升高(P<0.05),而SF组虽也升高但与基础值比无显著差异(P>0.05),组间比较T2~T4时点F组SBP、DBP、HR明显高于SF组(P<0.05)。结论舒芬太尼用于全麻诱导对双腔支气管插管引起的心血管反应抑制作用比芬太尼的效力强,插管期间患者血流动力更平稳。

Objective To compare the effects of sufentanil with fentanyl on relieving cardiovasucular response to intubation with double-lumen tubes.Methods Sixty ASAⅠ～Ⅱpatients undergoing selective thoracis surgery requiring intubation with double-lumen tubes were randomly divided into two groups with 30 cases each,sufentanil(group SF,0.3 μg/kg) or fentanyl(group F,3 μg/kg) was injected intervenously for anesthesia induction.The systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate(HR),were recorded be...