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Surgical Treatment of Recurrent Hepatocellular Carcinoma (A report of 112 cases)

Surgical Treatment of Recurrent Hepatocellular Carcinoma (A report of 112 cases)
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摘要 Objective The aim of this study was to evaluate the long term results of treatment and prognositic factors in patients with recurrent hepatocellular carcinoma after curative resection of hepatocellular carcinoma. Methods 112 patients of recurrent hepatocellular carcinoma who underwent surgical treatment were studied. Survival results after recurrence and from first hepatectomy were analyzed, and prognostic factors were determined by analyzing the clinicopathological variables.Results The mean survival of 112 patients was 26 months (4 to 76 months). 30 patients with tumor free state were still living. 1 year, 3 year and 5 year survival rates were 81.0%, 43.3% and 32 0%, respectively, and the 58 patients with hepatic resection were 87%, 59% and 38%, respectively. Among the 9 patients with secondary re resection, 6 had lived for over 3 years, and two for over 5 years. There were no operative death in this series, and few complications were found.Conclusion Early detection of recurrence depends on AFP measurements and ultrasonography follow up monitoring after resection. Re resection for recurrent hepatocellular carcinoma has been proved to be the most effective treatment modality. Aggressive treatment with a multimodality strategy is an option to improve long term survival in some patients with unresectable recurrent hepatocellular carcinoma.\; Objective The aim of this study was to evaluate the long term results of treatment and prognositic factors in patients with recurrent hepatocellular carcinoma after curative resection of hepatocellular carcinoma. Methods 112 patients of recurrent hepatocellular carcinoma who underwent surgical treatment were studied. Survival results after recurrence and from first hepatectomy were analyzed, and prognostic factors were determined by analyzing the clinicopathological variables.Results The mean survival of 112 patients was 26 months (4 to 76 months). 30 patients with tumor free state were still living. 1 year, 3 year and 5 year survival rates were 81.0%, 43.3% and 32 0%, respectively, and the 58 patients with hepatic resection were 87%, 59% and 38%, respectively. Among the 9 patients with secondary re resection, 6 had lived for over 3 years, and two for over 5 years. There were no operative death in this series, and few complications were found.Conclusion Early detection of recurrence depends on AFP measurements and ultrasonography follow up monitoring after resection. Re resection for recurrent hepatocellular carcinoma has been proved to be the most effective treatment modality. Aggressive treatment with a multimodality strategy is an option to improve long term survival in some patients with unresectable recurrent hepatocellular carcinoma.\;
出处 《Journal of Nanjing Medical University》 2000年第1期34-38,共5页 南京医科大学学报(英文版)
关键词 recurrence hepatocellular carcinoma surgical treatment recurrence hepatocellular carcinoma surgical treatment
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参考文献8

  • 1[1]Izumi R,Shimizu K,Ii T,et al.Prognostic factors of hepatocellular carcinoma in patients undergoing hepatic resection.Gastroenterology,1994,106(3):720
  • 2[2]Belghiti J,Panis Y,Farges O,et al.Intrahepatic recurrence after resection of hepatocellular carcinoma complicating cirrhosis.Ann Surg,1991,214(2):114
  • 3[3]Shimada M,Takenaka K,Taguchi K,et al.Prognostic factors after repeat hepatectomy for recurrent hepatocellular carcinoma.Ann Surg,1998,227(1):80
  • 4[4]Takenaka K,Adachi E,Nishizaki T,et al.Possible multicentric occurrence of hepatocelular carcinoma:a clinicopothological study.Hepatology,1994,19(4):889
  • 5[5]Hsu HC,Chiou T J,Chen JY,et al.Clonality and clonal and clonal evolution of hepatocellular carcinoma with multiple nodules.Hepatology,1991,13(5):932
  • 6[6]Nagasue N,Kohno H,Hayashi T,d al.Repeat hepatectomy for recurrent hepatocellular carcinoma.Br J Surg,1996,83(1):127
  • 7[7]Zhou XD,Tang ZY,Yu YQ,er al.Surgical treatment of recurrent hepatocellular carcinoma.HepatoGastroenternol,1993,40(4):333
  • 8[8]Takenaka K,Yoshida,Nishizaki T,et al.Postoperative prophylactic lipiodolization reduces the intrahepatic recurrence of hepatocellular carcinoma.Am J Surg,1995,169(4):400

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