50例支气管肺炎患儿心肌酶谱的检测观察

Assessment of Concentrations of Serum Myocardial Enzymes in 50 Children with Bronchopneumonia

目的:观察支气管肺炎患儿心肌酶谱改变并探讨缺氧和心肌损害的关系。方法:检测了50例无心力衰竭表现的支气管肺炎患儿的经皮血氧饱和度(TcSO_2)、心肌酶谱及心电图。结果:支气管肺炎患儿有不同程度的心肌酶升高,TcSO_2≤94％的肺炎组患儿和TcSO_2>94％的肺炎组患儿心肌酶CK、CK-MB、LDH、LDH_1、HBDH的值有显著性差异,前者显著高于后者(P<0.05)。结论:支气管肺炎患儿即使未出现心力衰竭表现,心肌也已遭受损害,且缺氧严重的患儿心肌损害的程度更重。因此积极治疗小儿支气管肺炎的同时,应及早使用心肌保护药物。

Objective: To assess concentrations of serum myocardial enzymes in children with bronchopneumonia and investigate the relationship between the damage of cardiac muscle and hypoxia. Methods: We measured the TcSO_2, concentrations of serum myocardial enzymes ( AST, CK, CK-MB, LDH, LDH-1, HBDH) and electrocardiogram in 50 children with bronchopneumonia. Results: The concentrations of serum myocardial enzymes were elevated in some children and the mean concentration of CK、CK-MB、LDH、LDH-1、HBDH in children whose TcSO_2≤94% was significantly higher than that in children whose TcSO_2>94% (P<0.05). Conclusion: It indicated that the damage of cardiac muscle was exist in children with bronchopneumonia complicating no heart failure symptom. The degree of damage was related to hypoxia. We should use drugs to protect cardiac muscle when we treat the children with bronchopneumonia.