能量多普勒及肿瘤标志物对卵巢癌的诊断与术后随访价值

The diagnostic validity of color Doppler energy and serum CA125、CEA、AFP in ovarian cancer and follow-up survey After the operation

目的:研究彩色多普勒能量图及血清肿瘤标志物CA125、癌胚抗原(CEA)、甲胎蛋白(AFP)诊断卵巢癌的价值及术后随访中的意义.方法:取术后病理确诊的卵巢癌40例,并以40例良性肿瘤为对照组,两组术前均行彩色多普勒能量图以及血清肿瘤标志物CA125、CEA、AFP测定.结果:卵巢良性肿瘤以周边环状及星点状血流为主,恶性肿瘤则以内部血流为主.多普勒能量图半定量评分判断恶性卵巢肿瘤敏感性90.0%,特异性87.5%.肿瘤标志物:以CA125≥35U/ml和/或AFP≥10ng/ml和/或CEA≥5ng/ml判断为恶性,敏感性67.5%,特异性83.3%.多普勒能量图及肿瘤标志物CA125、AFP、CEA联合检测,敏感性95.0%,特异性92.5%.结论:多普勒能量图与肿瘤标志物联合检查对鉴别卵巢良恶性肿瘤有重要价值,可提高术前确诊率,是诊断早期卵巢癌较好的方法.术后随访及预测肿瘤的复发和转移,肿瘤标志物较能量多普勒更敏感.

Objective: To explore the diagnostic validity of color Doppler energy (CDE) and serum CA125?CEA?AFP in ovarian cancer and follow-up survey After the operation. Methods: 40 cases with ovarian cancer confirmed by postoperative histopathology and 40 cases with ovarian Benign tumor were examined using CDE and serum CA125?CEA?AFP. Results: The blood flow of the benign parenchyma tumor in ovary was the asterism shape. The blood flow sign in the malignant tumor in ovary was characteristic of by internal blood stream primarily. The sensitivity of CDE with half quantitative analysis to grade malignant tumor in ovary was 90.0%, the Specificity of it was 87.5%. The sensitivity of tumor markers to grade malignant tumor in ovary was 67.5%, the Specificity of it was 83.3%. The sensitivity of union inspection with CDE and tumor markers was 95.0%, the Specificity of it was 92.5%. Conclusion: The union inspection with CDE and tumor markers had important diagnostic validity in ovarian cancer. The tumor markers were more Sensitive compared to CDE in forecast tumor recursing and Shifting follow-up survey After the operation.